Business innovation is a process that requires creativity, and benefits from extensive collaboration.Currently, computational support in creativity processes is low, but modern techniques would allow these processes to be sped up.In this context, we provide such a computational support with software for business innovation design that uses computat
The CDKN1B gene encodes for the p27Kip1 protein, firstly characterized as a cyclin dependent kinase (CDK)-inhibitor.Germline CDKN1B pathogenic variants have been described in hereditary tumors, such as multiple endocrine neoplasia (MEN)-like syndromes and familial prostate cancer.Despite its central role in tumor progression, for a long time it has
This article explores the design and application of machine learning techniques to enhance traditional approaches for solving NP-hard optimization problems.Specifically, it focuses on the Last-Mile Routing Research Challenge (LMRRC), supported by Amazon and MIT, which sought innovative solutions for cargo routing optimization.While the challenge se